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[57] demonstrated that GLP-1 based agents were associated with a three-fold increased risk of pancreatic enzyme elevation relative to controls, yet did not indicate a significant rise in pancreatitis or pancreatic cancer

'If you find something, it will take many years and lots of money to get something that is approved as a drug to use on humans.' Exenatide (commercial name Byetta), the synthetic version of exendin-4, was developed in 1992 but was not approved for use until 2005

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Since the intersection of orthopedics with other subjects, we also supported the application of nano-biomaterials, bacterial synthetic biology, and novel small molecules in anti-osteoporosis, which is expected to unlock broader prospects for the multidisciplinary integration of the gutbone axis