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qPCR-based microarray using total RNA isolated from hippocampal tissues of non-Tg, vehicle-fed, and Hex-fed 5XFAD mice was performed as described previously (9, 47)
A single contained HPAPI manufacturing suite, including isolator-protected synthesis and purification equipment, HEPA-filtered dedicated HVAC, negative-pressure containment, and validated cleaning and containment verification protocols, costs $50 million to $150 million to build and validate
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