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What matters is whether something other than intake is behind the result

Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition where the immune system destroys self, in this case the parietal cells of the stomach

If we know the amount of B12 absorbed from various supplemental doses of cyanocobalamin, we can create recommendations to meet the predicted amount of B12 absorbed per week by the IOM and EFSA recommendations