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A 2025 systematic review of orthopaedic sports-medicine research involving BPC-157 (Vasireddi et al.) identified the absence of human randomized clinical trials and noted that the reported tendon-related findings derive almost entirely from rodent preparations conducted by a small number of collaborating laboratories [11]

Generative AI and AI-assisted technologies During the preparation of this work, the author(s) used Grammarly to improve language clarity and correct grammatical errors

Author contributions Authors responsible for concept and design were MJH, HTL, HYH, YL, and JHSP

Serious adverse events were rare and not dose-dependent