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Common thyroid conditions such as hypothyroidism or Hashimoto's are not contraindications, though thyroid status should be optimized and monitored

Its just a coincidence that they found an effect in diabetes first. Kariya and other companies are now pursuing the use of these drugs to treat neurodegeneration

Express Scripts requires BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease)

There have also been documented local skin reactions when using GLP-1 RAs, particularly with the long-acting formulations