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A recent study combining single-nucleus sequencing and spatial transcriptomics pinpointed the human hypothalamic GLP-1R-LepR co-expressing cluster, which strongly correlated with the mouse hypothalamic cluster that exhibits the second highest expression of GLP-1R in the hypothalamus [76]
These particles were subsequently subjected to CTF refinement and Bayesian polishing, which generated a map with an indicated global resolution of 3.4
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