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The hyperglycaemic effect of glucagon may depend both on glycogenolysis in a dose-dependent manner, mediated through cAMP and on transcription-dependent changes in rate-limiting gluconeogenic enzymes, such as PEPCK

Its reduced form, commonly abbreviated to GSH, participates in redox regulation, peroxide metabolism, protein-thiol protection and the handling of numerous reactive compounds

Short-term storage at 2-8C (refrigerated) is acceptable for peptides that will be used within weeks

Once opened, a multi-dose vial can generally be used for up to 28 days , provided it is stored correctly and accessed using sterile technique