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A genuine improvement in energy typically sets in over roughly 12 to 48 hours as your body's energy metabolism becomes more efficient
No dosing or administration guidelines are provided
Older adults often produce less stomach acid, which is necessary to release B12 from food
The liver stores are a bit irrelevant to someone who has PA or a B12 absorption problem though because the mechanism that is used to release them relies on the same mechanism that is used to absorb most dietary B12 so accessing any stores is at best very inefficient
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