Once Sahagin has been blocked, casting a noncreature spell in order to cause Sahagin's ability to trigger won't cause Sahagin to become unblocked
Set Number 363 Language Portugus Legal Formats Commander, Historic, Legacy, Vintage Not Legal Formats Alchemy, Brawl, Competitive Brawl, Modern, Pauper, Pioneer, Standard, Timeless Rulings (6/10/2022) If there is no legal target for the reflexive trigger in Minsc & Boo's second loyalty ability, or if the target is illegal as the ability tries to resolve, you will not draw any cards even if the sacrificed creature was a Hamster
Ulamog, the Defiler (Retro Foil) $76.99 Most Eldrazi titans create prohibitive board states and totally flip the advantage, even if most of these cards have high mana costs
Vaevictis' pump effect can also be relevant, but poor Palladia gets the short end of the stick - she's just a very big, trample-y dragon